Cart
sales@molnova.com
Home - Products - MAPK/ERK Signaling - Ras - Deltasonamide 1

Deltasonamide 1

CAS No. 2088485-33-8

Deltasonamide 1( Deltasonamide1 )

Catalog No. M13257 CAS No. 2088485-33-8

A novel small molecule inhibitor of PDE6δ/KRas interaction with Kd of 203 pM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 582 Get Quote
50MG 2322 Get Quote
100MG 3060 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Deltasonamide 1
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel small molecule inhibitor of PDE6δ/KRas interaction with Kd of 203 pM.
  • Description
    A novel small molecule inhibitor of PDE6δ/KRas interaction with Kd of 203 pM; inhibits PDE6δ/KRas interaction in cells with Kd of 85 nM, selectively inhibits growth of KRas mutated and -dependent cells.
  • In Vitro
    Cell Proliferation Assay Cell Line:RTCA of hPDAC cell lines.Concentration:0.375, 0.75, 1.5, 3, 6, 12 μM.Incubation Time:60 h.Result:Inhibited proliferation of human pancreatic cancer cell lines.
  • In Vivo
    ——
  • Synonyms
    Deltasonamide1
  • Pathway
    MAPK/ERK Signaling
  • Target
    Ras
  • Recptor
    Ras
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2088485-33-8
  • Formula Weight
    647.25
  • Molecular Formula
    C30H39ClN6O4S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 66.67 mg/mL (103.01 mM)
  • SMILES
    O=S(C1=CC=C(S(=O)(N(CC2=NC(NC)=NC=C2)CC3CCNCC3)=O)C=C1)(N(CC4=CC=C(Cl)C=C4)C5CCCC5)=O
  • Chemical Name
    N1-(4-chlorobenzyl)-N1-cyclopentyl-N4-((2-(methylamino)pyrimidin-4-yl)methyl)-N4-(piperidin-4-ylmethyl)benzene-1,4-disulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Martín-Gago P, et al. Angew Chem Int Ed Engl. 2017 Feb 20;56(9):2423-2428.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Deltazinone 1

    Deltazinone 1 (Deltazinone1)?is a novel highly selective PDEδ inhibitor that inhibits PDEδ/Ras interaction with Kd of 8±4 nM.

  • MRTX849

    MRTX849 is a potent selective and covalent KRASG12C inhibitor with potential antineoplastic activity.selectively modifies mutant cysteine 12 in GDP-bound KRASG12C and inhibits KRAS-dependent signaling.

  • ARS-1630

    ARS-1630 is the R-conformational atropisomer of ARS-1620.

Sign In Join Free